Parkinson's disease: The quintessential neuropsychiatric disorder
Identifieur interne : 000039 ( Main/Corpus ); précédent : 000038; suivant : 000040Parkinson's disease: The quintessential neuropsychiatric disorder
Auteurs : Daniel Weintraub ; David J. BurnSource :
- Movement Disorders [ 0885-3185 ] ; 2011-05.
English descriptors
- KwdEn :
Abstract
Although diagnosed by characteristic motor features, Parkinson's disease may be preceded, and is frequently accompanied by, a wide range of cognitive and neuropsychiatric features. In addition to the most commonly studied disorders of dementia, depression, and psychosis, other relatively common and clinically significant psychiatric complications include impulse control disorders, anxiety symptoms, disorders of sleep and wakefulness, and apathy. These problems may be underrecognized and are frequently undertreated. The emergent focus on nonmotor aspects of Parkinson's disease over the past quarter of a century is highlighted by a nonlinear increase in the number of articles published devoted to this topic. Although the development of newer antidepressants, atypical antipsychotics, and cholinesterase inhibitors in recent years has had a positive benefit on the management of these troublesome and distressing symptoms, responses are frequently suboptimal, and this remains an area of major unmet therapeutic need. © 2011 Movement Disorder Society
Url:
DOI: 10.1002/mds.23664
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ISTEX:8B43FCB24250ADC27534FC0218A5F01E8201250BLe document en format XML
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Full financial disclosures and author roles may be found in the online version of this article.</note><subject lang="en"><genre>Keywords</genre><topic>Parkinson's</topic><topic>dementia</topic><topic>neuropsychiatric</topic><topic>depression</topic><topic>psychosis</topic></subject><relatedItem type="host"><titleInfo><title>Movement Disorders</title></titleInfo><titleInfo type="abbreviated"><title>Mov. 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